产品货号：
Z21662
中文名称：
NALP12抗体
英文名称：
Anti-NALP12 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-NALP12 Antibody |
| 指标别名 | RNO,PAN6,RNO2,FCAS2,NALP12,PYPAF7,CLR19.3,RNO,NACHT,LRR and PYD domains-containing protein 12,Monarch-1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | NLRP12 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | NALP12 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human NALP12.The immunogen is located within amino acids 110 - 160 of NALP12. |
| 计算分子量 | 120kDa |
| 成分 | NALP12 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | NALP12 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction.Like all other NALP family members,NALP12,also known as Monarch-1,has a C-terminal leucine-rich repeat (LRR) region,an N-terminal Pyrin domain (PYD) followed by a NACHT domain,and a NACHT-associated domain.NALP12 is thought to act as an attenuating factor of inflammation by suppressing inflammatory responses such as NF-百B activation by TLR-signaling molecules MyD88,IRAK-1,TRAF6 and RIPK1 in activated monocytes.Recent evidence suggests that mutations in NALP12 result in hereditary periodic fever syndromes. |
| Uniprot ID | P59046 |
| 基因名全称 | NLR family,pyrin domain containing 12 |
| 蛋白名全称 | NLR family,pyrin domain containing 12 |
| 推荐稀释比 | NALP12 antibody can be used for detection of NALP12 by Western blot at 1μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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